IDENTIFICATION OF BARRIERS AND FACILITATORS TO HIV PRE-EXPOSURE PROHYLAXIS (PREP) USE IN GAY AND BISEXUAL MEN
##plugins.themes.bootstrap3.article.main##
Abstract
Background: Objectives: The COM-B model of capability, motivation, and opportunity was used to estimate the determinants of PrEP usage intention among men who have sex with men (MSM). Methods: Fourteen semi-structured interviews were conducted with MSM recruited through snowball sampling. The interviews lasted 30-60 minutes and were conducted via Zoom or telephone. The data were analyzed using Atlas Ti v.8 and mapped to capability, motivation, and opportunity domains. Results: Potential facilitators identified were the skills and interest in seeking information about PrEP (capability), social support and peer opinion (opportunity), and motivations to use PrEP as an additional tool in HIV prevention. The main barriers identified were stigma towards homosexuality and HIV (opportunity); healthcare system organization and financing (opportunity); perceived lack of ability to adhere to PrEP usage (capability); and monitoring of PrEP that could be attributed to personal and healthcare system factors (capability and opportunity). Conclusions: Four strategies are suggested to address these barriers: 1) adaptation of interventions that promote knowledge and skills for PrEP; 2) development of navigator interventions to engage organizations and leaders; 3) education and skills training for primary care physicians; and 4) improvement of sexual health care systems.
##plugins.themes.bootstrap3.article.details##
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
openAccess
Alvarado, B. E., Martinez-Cajas, J. L., Mueses, H. F., Correa Sanchez, D., Adam, B. D., & Hart, T. A. (2021). Adaptation and Pilot Evaluation of an Intervention Addressing the Sexual Health Needs of Gay Men Living with HIV Infection in Colombia. American Journal of Men’s Health, 15(1). https://doi.org/10.1177/1557988321989916
Alves Dos Santos, L., Grangeiro, A., & Couto, M. T. (2022). HIV Pre-Exposure Prophylaxis (PrEP) among men who have sex with men: peer communication, engagement and social networks. Ciencia e Saude Coletiva, 27(10), 3923–3937. https://doi.org/10.1590/1413-812320222710.06542022EN
Andriano, T. M., Arnsten, J., & Patel, V. V. (2022). Social determinants of health and HIV PreExposure Prophylaxis (PrEP) interest and use among young Black and Latinx sexual minority men. PLoS ONE, 17(4 April). https://doi.org/10.1371/journal.pone.0267031
Arrivillaga, M., Gómez, S. A., Mueses, H. F., Alvarado, B., Buitrago, E. M., Camargo-Plazas, P., Hurtado, L. R., Bolívar, M. C., Galindo, X., Torres, J., & Cajas-Martínez, J. L. (2022). Facilitators and Recommendations of Health Care Providers for the Implementation of Pre-Exposure Prophylaxis in HIV clinics in Colombia. “PrEP-Colombia Study.” Revista Gerencia y Politicas de Salud, 21. https://doi.org/10.11144/Javeriana.rgps21.frps
Assaf, R. D., Konda, K. A., Torres, T. S., Vega-Ramirez, E. H., Elorreaga, O. A., Diaz-Sosa, D., Diaz, S. D., Pimenta, C., Robles, R., Medina-Mora, M. E., Grinsztejn, B., Caceres, C., & Veloso, V. G. (2021). Are men who have sex with men at higher risk for HIV in Latin America more aware of PrEP? PLoS ONE, 16(8 August), e0255557. https://doi.org/10.1371/journal.pone.0255557
Berbersi Fernández, D. Y. (2019). Vulnerabilidad al VIH y prevalencia de VIH en mujeres transgénero en tres ciudades de Colombia?: Bogotá, Medellín y Santiago de Cali, 2019.
Beymer, M. R., Gildner, J. L., Holloway, I. W., & Landovitz, R. J. (2018). Acceptability of injectable and on-demand pre-exposure prophylaxis among an online sample of young men who have sex with men in California. LGBT Health, 5(6), 341–349. https://doi.org/10.1089/lgbt.2017.0244
Biello, K. B., Bazzi, A. R., Mimiaga, M. J., Biancarelli, D. L., Edeza, A., Salhaney, P., Childs, E., & Drainoni, M. L. (2018). Perspectives on HIV pre-exposure prophylaxis (PrEP) utilization and related intervention needs among people who inject drugs 16 Studies in Human Society 1608 Sociology. Harm Reduction Journal, 15(1). https://doi.org/10.1186/s12954-018-0263-5
Blair, K. J., Segura, E. R., Garner, A., Lai, J., Ritterbusch, A., Leon-Giraldo, S., Guilamo-Ramos, V., Lake, J. E., Clark, J. L., & Holloway, I. W. (2021). Pre-exposure prophylaxis awareness, use, and intention to use in a regional sample of Latin American geosocial networking application users in 2018–2019. International Journal of STD and AIDS, 32(13), 1261–1267. https://doi.org/10.1177/09564624211034618
Calabrese, S. K., & Underhill, K. (2015). How Stigma Surrounding the Use of HIV Preexposure Prophylaxis Undermines Prevention and Pleasure: A Call to Destigmatize “Truvada Whores.” American Journal of Public Health, 105(10), 1960–1964. https://doi.org/10.2105/AJPH.2015.302816
Ching, S. Z., Wong, L. P., Said, M. A. B., & Lim, S. H. (2020). Meta-synthesis of qualitative research of pre-exposure prophylaxis (Prep) adherence among men who have sex with men (msm). AIDS Education and Prevention, 32(5), 416–431. https://doi.org/10.1521/aeap.2020.32.5.416
Corporación de Lucha Contra el Sida. (2021). INFORME DESCRIPTIVO RESULTADOS CUALITATIVOS ENTREVISTAS A POBLACIÓN A RIESGO. https://cls.org.co/proyecto-prep/
Dubov, A., Altice, F. L., & Fraenkel, L. (2018). An Information–Motivation–Behavioral Skills Model of PrEP Uptake. AIDS and Behavior, 22(11), 3603–3616. https://doi.org/10.1007/s10461-018-2095-4
Dubov, A., Galbo, P., Altice, F. L., & Fraenkel, L. (2018). Stigma and Shame Experiences by MSM Who Take PrEP for HIV Prevention: A Qualitative Study. American Journal of Men’s Health, 12(6), 1843–1854. https://doi.org/10.1177/1557988318797437
Emmanuel, G., Folayan, M., Undelikwe, G., Ochonye, B., Jayeoba, T., Yusuf, A., Aiwonodagbon, B., Bilali, C., Umoh, P., Ojemeiri, K., & Kalaiwo, A. (2020). Community perspectives on barriers and challenges to HIV pre-exposure prophylaxis access by men who have sex with men and female sex workers access in Nigeria. BMC Public Health, 20(1), 1–10. https://doi.org/10.1186/s12889-020-8195-x
Hillis, A., Germain, J., Hope, V., McVeigh, J., & Van Hout, M. C. (2020). Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among Men Who Have Sex with Men (MSM): A Scoping Review on PrEP Service Delivery and Programming. AIDS and Behavior, 24(11), 3056–3070. https://doi.org/10.1007/s10461-020-02855-9
Kadiamada-Ibarra, H., Hawley, N. L., Sosa-Rubí, S. G., Wilson-Barthes, M., Galárraga, O., & Franco, R. R. (2021). Barriers and facilitators to pre-exposure prophylaxis uptake among male sex workers in Mexico: an application of the RE-AIM framework. BMC Public Health, 21(1). https://doi.org/10.1186/s12889-021-12167-9
Koester, K., Amico, R. K., Gilmore, H., Liu, A., McMahan, V., Mayer, K., Hosek, S., & Grant, R. (2017). Risk, safety and sex among male PrEP users: time for a new understanding. Culture, Health & Sexuality, 19(12), 1301–1313. https://doi.org/10.1080/13691058.2017.1310927
Konda, K. A., Torres, T. S., Mariño, G., Ramos, A., Moreira, R. I., Leite, I. C., Cunha, M., Jalil, E. M., Hoagland, B., Guanira, J. V., Benedetti, M., Pimenta, C., Vermandere, H., Bautista-Arredondo, S., Vega-Ramirez, H., Veloso, V. G., Caceres, C. F., & Grinsztejn, B. (2022). Factors associated with long-term HIV pre-exposure prophylaxis engagement and adherence among transgender women in Brazil, Mexico and Peru: results from the ImPrEP study. Journal of the International AIDS Society, 25(S5), e25974. https://doi.org/10.1002/jia2.25974
Madhani, A., & Finlay, K. A. (2022). Using the COM-B model to characterize the barriers and facilitators of pre-exposure prophylaxis (PrEP) uptake in men who have sex with men. British Journal of Health Psychology, 27(4), 1330–1353. https://doi.org/10.1111/bjhp.12605
Mainville, S., & Deslauriers, J.-P. (1992). Recherche qualitative: guide pratique. Canadian Journal of Education / Revue Canadienne de l’éducation, 17(4), 466. https://doi.org/10.2307/1495447
Martinez-Cajas, J. L., Torres, J., Mueses, H. F., Plazas, P. C., Arrivillaga, M., Gomez, S. A., Galindo, X., Buitrago, E. M., & Llano, B. E. A. (2022). Applying implementation science frameworks to identify factors that influence the intention of healthcare providers to offer PrEP care and advocate for PrEP in HIV clinics in Colombia: a cross-sectional study. Implementation Science Communications, 3(1), 1–14. https://doi.org/10.1186/s43058-022-00278-2
Michie, S., van Stralen, M. M., & West, R. (2011). The behaviour change wheel: A new method for characterising and designing behaviour change interventions. Implementation Science, 6(1), 1–12. https://doi.org/10.1186/1748-5908-6-42
Mueses-Marín, H. F., Alvarado-Llano, B., Torres-Isasiga, J., Camargo-Plazas, P., Bolívar-Rocha, M. C., Galindo-Orrego, X., & Martínez-Cajas, J. L. (2021). Scales to Assess Knowledge, Motivation, and Self-Efficacy for HIV PrEP in Colombian MSM: PrEP-COL Study. AIDS Research and Treatment, 2021, 1–11. https://doi.org/10.1155/2021/4789971
Mueses-Marín HF, et al. (2024). Uso de Profilaxis Preexposición al VIH: interés e intención en hombres gay y/o bisexuales, Colombia. Hacia Promoc Salud.
Murchu, E., Marshall, L., Teljeur, C., open, P. H.-B., & 2022, undefined. (2022). Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all. Bmjopen.Bmj.ComEO Murchu, L Marshall, C Teljeur, P Harrington, C Hayes, P Moran, M RyanBMJ Open, 2022•bmjopen.Bmj.Com, 12, 48478. https://doi.org/10.1136/bmjopen-2020-048478
Philbin, M. M., Parker, C. M., Parker, R. G., Wilson, P. A., Garcia, J., & Hirsch, J. S. (2016). The Promise of Pre-Exposure Prophylaxis for Black Men Who Have Sex with Men: An Ecological Approach to Attitudes, Beliefs, and Barriers. AIDS Patient Care and STDs, 30(6), 282–290. https://doi.org/10.1089/apc.2016.0037
Ramanaik Id, S., Pradhan Sinha, A., Mukherjee, A., Pujar, A., Subramanyam, K., Gopalan, A., & Washington, R. (2023). Acceptability of PrEP among MSM and transgender communities—Qualitative findings from two metropolitan cities in India. Journals.Plos.OrgS Ramanaik, AP Sinha, A Mukherjee, A Pujar, K Subramanyam, A Gopalan, R WashingtonPlos One, 2023•journals.Plos.Org, 18(2 February). https://doi.org/10.1371/journal.pone.0281984
Ravasi, G., Grinsztejn, B., Baruch, R., Guanira, J. V., Luque, R., Cáceres, C. F., & Ghidinelli, M. (2016). Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America. In Journal of the International AIDS Society (Vol. 19, Issue 7(Suppl 6)). J Int AIDS Soc. https://doi.org/10.7448/IAS.19.7.21113
Rhodes, S. D., Alonzo, J., Mann-Jackson, L., Song, E. Y., Tanner, A. E., Garcia, M., Smart, B. D., Baker, L. S., Eng, E., & Reboussin, B. A. (2020). A peer navigation intervention to prevent HIV among mixed immigrant status Latinx GBMSM and transgender women in the United States: Outcomes, perspectives and implications for PrEP uptake. Health Education Research, 35(3), 165–178. https://doi.org/10.1093/her/cyaa010
Sidebottom, D., Ekström, A. M., & Strömdahl, S. (2018). A systematic review of adherence to oral pre-exposure prophylaxis for HIV – how can we improve uptake and adherence? BMC Infectious Diseases 2018 18:1, 18(1), 1–14. https://doi.org/10.1186/S12879-018-3463-4
Torres, T. S., Konda, K., Vega-Ramirez, E. H., Elorreaga Reyes, O. A., Diaz-Sosa, D., Hoagland, B., Diaz, S., Pimenta, C., Bennedeti, M., Lopez-Gatell, H., Robles-Garcia, R., Grinsztejn, B., Caceres, C., & Veloso, V. G. (2019). Awareness and factors associated with willingness to use Pre-exposure prophylaxis (PrEP) in Brazil, Mexico and Peru: an online survey among men who have sex with men (MSM) (Preprint). JMIR Public Health and Surveillance, 5(2), e13771. https://doi.org/10.2196/13771
Torres, T. S., Marins, L. M. S., Veloso, V. G., Grinsztejn, B., & Luz, P. M. (2019). How heterogeneous are MSM from Brazilian cities? An analysis of sexual behavior and perceived risk and a description of trends in awareness and willingness to use pre-exposure prophylaxis. BMC Infectious Diseases, 19(1). https://doi.org/10.1186/s12879-019-4704-x
Tracy, S. J. (2010). Qualitative quality: Eight a"big-tent" criteria for excellent qualitative research. Qualitative Inquiry, 16(10), 837–851. https://doi.org/10.1177/1077800410383121
Underhill, K., Morrow, K. M., Colleran, C., Holcomb, R., Calabrese, S. K., Operario, D., Galárraga, O., & Mayer, K. H. (2015). A Qualitative Study of Medical Mistrust, Perceived Discrimination, and Risk Behavior Disclosure to Clinicians by U.S. Male Sex Workers and Other Men Who Have Sex with Men: Implications for Biomedical HIV Prevention. Journal of Urban Health, 92(4), 667–686. https://doi.org/10.1007/s11524-015-9961-4
Walsh, J. L. (2019). Applying the Information–Motivation–Behavioral Skills Model to Understand PrEP Intentions and Use Among Men Who Have Sex with Men. AIDS and Behavior, 23(7), 1904–1916. https://doi.org/10.1007/s10461-018-2371-3
Zucchi, E. M., Couto, M. T., Castellanos, M., Dumont-Pena, É., Ferraz, D., Pinheiro, T. F., Grangeiro, A., da Silva, L. A. V., Dourado, I., Pedrana, L., de Resende Santos, F. S., & Magno, L. (2021). Acceptability of daily pre-exposure prophylaxis among adolescent men who have sex with men, travestis and transgender women in Brazil: A qualitative study. PLoS ONE, 16(5 May). https://doi.org/10.1371/journal.pone.0249293